Glomerular Hyperfiltration and Renal Disease Progression in Type 2 Diabetes

To describe the prevalence and determinants of hyperfiltration (glomerular filtration rate [GFR] ≥120 mL/min/1.73 m(2)), GFR decline, and nephropathy onset or progression in type 2 diabetic patients with normo- or microalbuminuria. We longitudinally studied 600 hypertensive type 2 diabetic patients...

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Veröffentlicht in:	Diabetes care 2012-10, Vol.35 (10), p.2061-2068
Hauptverfasser:	RUGGENENTI, Piero, PORRINI, Esteban L, ILIEV, Ilian, ROBERTO DODESINI, Alessandro, TREVISAN, Roberto, BOSSI, Antonio, ZALETEL, Jelka, REMUZZI, Giuseppe, GASPARI, Flavio, MOTTERLINI, Nicola, CANNATA, Antonio, CARRARA, Fabiola, CELLA, Claudia, FERRARI, Silvia, STUCCHI, Nadia, PARVANOVA, Aneliya
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Albuminuria - complications Biological and medical sciences Blood Glucose Cohort Studies Development and progression Diabetes Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance Diabetic Nephropathies - etiology Disease Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Glomerular Filtration Rate - physiology Humans Hypertension Kidney diseases Kidney Glomerulus - physiopathology Kidneys Male Medical research Medical sciences Medicine, Experimental Metabolic diseases Middle Aged Miscellaneous Original Research Public health. Hygiene Public health. Hygiene-occupational medicine Studies Type 2 diabetes
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Zusammenfassung:	To describe the prevalence and determinants of hyperfiltration (glomerular filtration rate [GFR] ≥120 mL/min/1.73 m(2)), GFR decline, and nephropathy onset or progression in type 2 diabetic patients with normo- or microalbuminuria. We longitudinally studied 600 hypertensive type 2 diabetic patients with albuminuria
ISSN:	0149-5992 1935-5548
DOI:	10.2337/dc11-2189