Changes in serum thymidine kinase 1 levels during chemotherapy correlate with objective response in patients with advanced gastric cancer

Changes in serum thymidine kinase 1 levels during chemotherapy correlate with objective response in patients with advanced gastric cancer

Serum thymidine kinase 1 (STK1) is a reliable proliferation marker in most solid tumors, including gastric cancer. The aim of this study was to evaluate whether STK1 levels are related to the tumor response to chemotherapy and survival in advanced gastric cancer. The results showed that the average...

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Veröffentlicht in:Experimental and therapeutic medicine 2011-11, Vol.2 (6), p.1177-1181
Hauptverfasser: LIU, YONGPING, LING, YANG, QI, QIUFENG, TANG, YEXIN, XU, JIANZHONG, TONG, ZHOU, SHENG, GUIFENG, YANG, QUANLIANG, PAN, YAODONG
Format: Artikel
Sprache:eng
Schlagworte:
chemotherapy
gastric cancer
objective response
survival
tumor marker
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Zusammenfassung:Serum thymidine kinase 1 (STK1) is a reliable proliferation marker in most solid tumors, including gastric cancer. The aim of this study was to evaluate whether STK1 levels are related to the tumor response to chemotherapy and survival in advanced gastric cancer. The results showed that the average STK1 level in patients with gastric cancer (5.57±3.07 pM) was significantly higher than that in the healthy controls (1.12±0.57) (P
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2011.338