Dielectric study of the interaction between DNA and an oligopeptide (lysine-tyrosinelysine)

Dielectric study of the interaction between DNA and an oligopeptide (lysine-tyrosinelysine)

Interaction between Na-DNA and the oligopeptide lysine-tyrosinelysine (LTL) is studied by a dielectric method. The comparison between conductivities (at the frequence of 5MHz) of LTL alone and of the complex LTL-DNA allows us to show up an electrostatic interaction between LTL and phosphates sites o...

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Veröffentlicht in:Nucleic acids research 1976-04, Vol.3 (4), p.1001-1012
Hauptverfasser: Rix-Montel, Marie-Agnès, Grassi, Henri, Vasilescu, Dane
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Binding Sites
Cattle
DNA
Electric Conductivity
Electrochemistry
Lysine
Mathematics
Oligopeptides
Protein Binding
Sodium Chloride
Spectrophotometry, Atomic
Thymus Gland
Tyrosine
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Zusammenfassung:Interaction between Na-DNA and the oligopeptide lysine-tyrosinelysine (LTL) is studied by a dielectric method. The comparison between conductivities (at the frequence of 5MHz) of LTL alone and of the complex LTL-DNA allows us to show up an electrostatic interaction between LTL and phosphates sites of DNA. During the formation of the complex LTL-DNA, acertain fraction of Na$ counter-ions is ejected from the phosphates sites.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/3.4.1001