Distribution of delta opioid receptor-expressing neurons in the mouse hippocampus

Graphical abstract Highlights ► Fluorescent knock-in mice were used to map delta opioid receptor distribution. ► Delta opioid receptors are present in all hippocampal areas. ► Hippocampal delta opioid receptors are primarily expressed in GABAergic neurons. ► Delta opioid receptors are mostly identif...

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Veröffentlicht in:	Neuroscience 2012-09, Vol.221, p.203-213
Hauptverfasser:	Erbs, E, Faget, L, Scherrer, G, Kessler, P, Hentsch, D, Vonesch, J.-L, Matifas, A, Kieffer, B.L, Massotte, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Female fluorescent knock-in mouse Fundamental and applied biological sciences. Psychology G protein-coupled receptor GABAergic neurons Glutamate Decarboxylase - metabolism Green Fluorescent Proteins - genetics Hippocampus - anatomy & histology Hippocampus - cytology Humans immunohistochemistry Male Mice Mice, Inbred C57BL Mice, Transgenic Nerve Tissue Proteins - metabolism Neurology Neurons - metabolism Parvalbumins - metabolism Receptors, Opioid, delta - genetics Receptors, Opioid, delta - metabolism Somatostatin - metabolism Vertebrates: nervous system and sense organs Vesicular Glutamate Transport Protein 1 - metabolism Vesicular Glutamate Transport Protein 2 - metabolism
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Beschreibung
Zusammenfassung:	Graphical abstract Highlights ► Fluorescent knock-in mice were used to map delta opioid receptor distribution. ► Delta opioid receptors are present in all hippocampal areas. ► Hippocampal delta opioid receptors are primarily expressed in GABAergic neurons. ► Delta opioid receptors are mostly identified in parvalbumin-positive neurons.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2012.06.023