Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature

Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature

Oxaliplatin in combination with a fluoropyrimide is a treatment option for colorectal cancer patients in the adjuvant and metastatic settings. Very few hematological emergencies have been reported associated with Oxaliplatin. These include autoimmune hemolytic anemia, thrombocytopenia and pancytopen...

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Veröffentlicht in:World journal of gastrointestinal oncology 2012-07, Vol.4 (7), p.181-183
Hauptverfasser: Kurian, Shweta, Macintyre, Jessica, Mushtaq, Muzammil, Rocha-Lima, Caio Max, Ahn, Yeon
Format: Artikel
Sprache:eng
Schlagworte:
cancer
Case Report
coagulation
colon
count
Disseminated
emergencies
Hematological
intravascular
Metastatic
Oxaliplatin
Platelet
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Zusammenfassung:Oxaliplatin in combination with a fluoropyrimide is a treatment option for colorectal cancer patients in the adjuvant and metastatic settings. Very few hematological emergencies have been reported associated with Oxaliplatin. These include autoimmune hemolytic anemia, thrombocytopenia and pancytopenia. We present a case report of a patient who developed hematuria and disseminated intravascular coagulation while receiving the second cycle of FOLFOX and bevacizumab for metastatic colon cancer.
ISSN:1948-5204
1948-5204
DOI:10.4251/wjgo.v4.i7.181