Local anesthetics: review of pharmacological considerations

Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. Their use is so routine, and adverse effects are so infrequent, that providers may understandably overlook many of their pharmacotherapeutic principles. The purpose of this continuing education articl...

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Veröffentlicht in:	Anesthesia progress 2012, Vol.59 (2), p.90-102
Hauptverfasser:	Becker, Daniel E, Reed, Kenneth L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Antagonists - pharmacology Anesthesia Recovery Period Anesthesia, Dental - methods Anesthesia, Local Anesthetics, Local - chemistry Anesthetics, Local - pharmacology Anesthetics, Local - toxicity Carticaine - pharmacology Continuing Education Drug Hypersensitivity Drug Interactions Humans Lidocaine - pharmacology Maximum Tolerated Dose Phentolamine - pharmacology Vasoconstrictor Agents - pharmacology
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Beschreibung
Zusammenfassung:	Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. Their use is so routine, and adverse effects are so infrequent, that providers may understandably overlook many of their pharmacotherapeutic principles. The purpose of this continuing education article is to provide a review and update of essential pharmacology for the various local anesthetic formulations in current use. Technical considerations will be addressed in a subsequent article.
ISSN:	0003-3006 1878-7177
DOI:	10.2344/0003-3006-59.2.90