Epigenetic impact of simulated maternal grooming on estrogen receptor alpha within the developing amygdala

Highlights ► Simulated maternal grooming influences sex differences in the developing amygdala. ► Females have more estrogen receptor alpha expression than males within the amygdala. ► Maternal care contributes to this sex difference by altering DNA methylation.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2011-10, Vol.25 (7), p.1299-1304
Hauptverfasser:	Edelmann, Michelle N, Auger, Anthony P
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Amygdala Amygdala - growth & development Amygdala - metabolism Animals Animals, Newborn Brain Development DNA Methylation Epigenesis, Genetic Epigenetic Estrogen receptor alpha Estrogen Receptor alpha - metabolism Female Grooming Male Maternal Behavior - physiology Maternal care Methylation Promoter Regions, Genetic Psychiatry Rats Rats, Sprague-Dawley RT-PCR Sex Characteristics Sexual differentiation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights ► Simulated maternal grooming influences sex differences in the developing amygdala. ► Females have more estrogen receptor alpha expression than males within the amygdala. ► Maternal care contributes to this sex difference by altering DNA methylation.
ISSN:	0889-1591 1090-2139
DOI:	10.1016/j.bbi.2011.02.009