statistical method for correlating tRNA sequence with amino acid specificity

A statistical method for finding the nucleotide positions in tRNA sequences that correlate with amino acid specificity has been developed. The procedure involves finding the subset of nucleotide positions and groups of positions where the marginal density of one amino acid tRNA class does not overla...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nucleic acids research 1986-01, Vol.14 (1), p.375-380
Hauptverfasser:	Atilgan, T, Nicholas, H.B. Jr, McClain, W.H
Format:	Artikel
Sprache:	eng
Schlagworte:	algorithms amino acids Amino Acids - genetics Applied sciences Base Sequence binding sites Biological and medical sciences computer analysis Computers Exact sciences and technology expectation maximization algorithm Fundamental and applied biological sciences. Psychology isoacceptor transfer rna Mathematics Molecular and cellular biology Molecular genetics nucleotide sequences Other techniques and industries RNA, Transfer - analysis RNA, Transfer, Amino Acyl - analysis Software statistical analysis transfer RNA Translation. Translation factors. Protein processing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A statistical method for finding the nucleotide positions in tRNA sequences that correlate with amino acid specificity has been developed. The procedure involves finding the subset of nucleotide positions and groups of positions where the marginal density of one amino acid tRNA class does not overlap that of any other amino acid class. The procedure is an application of a statistical method known as the Expectation Maximization algorithm.
ISSN:	0305-1048 1362-4962
DOI:	10.1093/nar/14.1.375