Paget’s disease of bone: a review of epidemiology, pathophysiology and management
Paget’s disease of bone is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. Fortunately, effective pharmacologic therapy, primarily with potent bisphosphonates, is now available to treat patients with co...
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Veröffentlicht in: | Therapeutic Advances in Musculoskeletal Disease 2009-12, Vol.1 (2), p.107-125 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Paget’s disease of bone is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. Fortunately, effective pharmacologic therapy, primarily with potent bisphosphonates, is now available to treat patients with complications or symptoms. This review of Paget’s disease of bone will include epidemiology and pathophysiology, complications and clinical findings, indications for treatment, and the drugs currently available to treat this condition. |
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ISSN: | 1759-720X 1759-7218 |
DOI: | 10.1177/1759720X09351779 |