SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons

Highlights ► Dopamine neurons of the substantia nigra express functional SK2 channels. ► SK2 is predominantly expressed in fine dendrites (

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2012-08, Vol.217, p.67-76
Hauptverfasser:	Deignan, J, Luján, R, Bond, C, Riegel, A, Watanabe, M, Williams, J.T, Maylie, J, Adelman, J.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Action potential Action Potentials - drug effects Action Potentials - physiology Animals Apamin - pharmacology Biological and medical sciences Dendrites Dopamine Dopaminergic Neurons - drug effects Dopaminergic Neurons - metabolism Dopaminergic Neurons - physiology Electrophysiological recording Firing rate Fundamental and applied biological sciences. Psychology Mice Mice, Knockout Microscopy Nervous system Neurology Neurons pacemaker Potassium channels (calcium-gated) Potassium conductance SK channels Small-Conductance Calcium-Activated Potassium Channels - genetics Small-Conductance Calcium-Activated Potassium Channels - metabolism spontaneous activity Substantia nigra Substantia Nigra - drug effects Substantia Nigra - metabolism Vertebrates: nervous system and sense organs
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Beschreibung
Zusammenfassung:	Highlights ► Dopamine neurons of the substantia nigra express functional SK2 channels. ► SK2 is predominantly expressed in fine dendrites (
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2012.04.053