Children of Persons With Alzheimer Disease : What Does the Future Hold?

Children of persons with Alzheimer disease (AD), as a group, face an increased risk of developing AD. Many of them, throughout their adult lives, seek input on how to reduce their chances of one day suffering their parent's fate. We examine the state of knowledge with respect to risk and protec...

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Veröffentlicht in:	Alzheimer disease and associated disorders 2008, Vol.22 (1), p.6-20
Hauptverfasser:	JARVIK, Lissy, LARUE, Asenath, FREIMER, Nelson, GOKHMAN, Izabella, MANLY, Jennifer J, PLASSMAN, Brenda L, RASGON, Natalie, ROBERTS, Jeffrey Scott, SUNDERLAND, Trey, SWAN, Gary E, WOLF, Phillip A, ZONDERMAN, Alan B, BLACKER, Deborah, GATZ, Margaret, KAWAS, Claudia, MCARDLE, John J, MORRIS, John C, MORTIMER, James A, RINGMAN, John M, ERCOLI, Linda
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alzheimer Disease - diagnosis Alzheimer Disease - genetics Biological and medical sciences Biomarkers Child Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Errors of metabolism Genetic Predisposition to Disease Humans Lipids (lysosomal enzyme disorders, storage diseases) Medical sciences Metabolic diseases Neurology Pedigree Risk Factors
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Zusammenfassung:	Children of persons with Alzheimer disease (AD), as a group, face an increased risk of developing AD. Many of them, throughout their adult lives, seek input on how to reduce their chances of one day suffering their parent's fate. We examine the state of knowledge with respect to risk and protective factors for AD and recommend a research agenda with special emphasis on AD offspring.
ISSN:	0893-0341 1546-4156
DOI:	10.1097/WAD.0b013e31816653ac