Simplified Insertion of Transgenes Onto Balancer Chromosomes via Recombinase-Mediated Cassette Exchange

Simplified Insertion of Transgenes Onto Balancer Chromosomes via Recombinase-Mediated Cassette Exchange

Balancer chromosomes are critical tools for Drosophila genetics. Many useful transgenes are inserted onto balancers using a random and inefficient process. Here we describe balancer chromosomes that can be directly targeted with transgenes of interest via recombinase-mediated cassette exchange (RMCE...

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Veröffentlicht in:G3 : genes - genomes - genetics 2012-05, Vol.2 (5), p.551-553
Hauptverfasser: Sun, Florence F, Johnson, Justine E, Zeidler, Martin P, Bateman, Jack R
Format: Artikel
Sprache:eng
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Investigations
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Zusammenfassung:Balancer chromosomes are critical tools for Drosophila genetics. Many useful transgenes are inserted onto balancers using a random and inefficient process. Here we describe balancer chromosomes that can be directly targeted with transgenes of interest via recombinase-mediated cassette exchange (RMCE).
ISSN:2160-1836
2160-1836
DOI:10.1534/g3.112.002097