Two BglII RFLPs of the human α-globin gene cluster in the American sickle cell population

Human alpha -globin cDNA cloned into plasmid pMB9 (JW101) was used as a hybridization probe for assessing the alpha -globin genotypes of 2271 Americans with sickle cell anemia.

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Bibliographische Detailangaben
Veröffentlicht in:	Nucleic acids research 1989-11, Vol.17 (21), p.8903-8903
Hauptverfasser:	EMBURY, S. H, BLACHMAN, T, KROPP, G. L, SUZUKI, J. K, BOYLE, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Sickle Cell - genetics Bacterial Proteins Biological and medical sciences Chromosomes, Human, Pair 16 Classical genetics, quantitative genetics, hybrids Cloning, Molecular Deoxyribonucleases, Type II Site-Specific DNA - genetics Fundamental and applied biological sciences. Psychology genes Genetics of eukaryotes. Biological and molecular evolution Globins - genetics Human Humans Multigene Family Plasmids Polymorphism, Restriction Fragment Length restriction fragment length polymorphism sickle cell disease
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Beschreibung
Zusammenfassung:	Human alpha -globin cDNA cloned into plasmid pMB9 (JW101) was used as a hybridization probe for assessing the alpha -globin genotypes of 2271 Americans with sickle cell anemia.
ISSN:	0305-1048 1362-4962