How does viral DNA find the nucleus of an infected cell?

If all locations of a living cell would have the same chemical potential, most viral infections of a cell should be abortive, even after the a penetration of the cell wall by the viral DNA-polymer or viral RNA-polymer occurred. This is obviously not the case. Therefore, there must be a mechanism whi...

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Veröffentlicht in:GMS Krankenhaushygiene interdisziplinär 2012-01, Vol.7 (1), p.Doc01-Doc01
1. Verfasser: Widulle, Herbert
Format: Artikel
Sprache:eng
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Zusammenfassung:If all locations of a living cell would have the same chemical potential, most viral infections of a cell should be abortive, even after the a penetration of the cell wall by the viral DNA-polymer or viral RNA-polymer occurred. This is obviously not the case. Therefore, there must be a mechanism which transports a viral DNA-polymer from the cell wall to the nucleus and not to any other location. A possible mechanism is proposed which is in accordance with biophysical chemistry. The presented description of the mechanism uses non equilibrium thermodynamics to find a simple solution for the problem.
ISSN:1863-5245
DOI:10.3205/dgkh000185