Anti - diabetic activity of the seed kernel of syzygium cumini linn
Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also b...
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| Veröffentlicht in: | Ancient science of life 1986-10, Vol.6 (2), p.80-84 |
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| container_title | Ancient science of life |
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| creator | Nair, R B Santhakumari, G |
| description | Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also be promoting endogenous release of insulin. An extra pancreatic site of action of the drug cannot be ruled out, since it produced a significant decrease in the blood sugar level (17.04%) in alloxan diabetic rats. |
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An extra pancreatic site of action of the drug cannot be ruled out, since it produced a significant decrease in the blood sugar level (17.04%) in alloxan diabetic rats.</description><subject>Original</subject><issn>0257-7941</issn><issn>2249-9547</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><recordid>eNpVkFtLw0AQhRdRbKn9C7KPvgT2fnkRSvEGBV_0OWyyk3Y12dRsUoi_3hSr6MzDwJnhO4c5Q3PGhM2sFPoczQmTOtNW0BlapvRGplKESmou0YwxKbWUbI7Wq9gHnGEfXAF9KLEr-3AI_YjbCvc7wAnA43foItRHKY2f4zYMDS6HJsSA6xDjFbqoXJ1geZoL9Hp_97J-zDbPD0_r1SbbU0rNlMWAorKiQnjinOFGS-ukN54AI6yQ0lTEUw6CUVsCn9oLrZSqWEVsYfgC3X5z90PRgC8h9p2r830XGteNeetC_n8Twy7ftoecc04FOQJuToCu_Rgg9XkTUgl17SK0Q8opmYJaZZWeTq__ev2a_HyOfwF_4Wtz</recordid><startdate>198610</startdate><enddate>198610</enddate><creator>Nair, R B</creator><creator>Santhakumari, G</creator><general>Medknow Publications & Media Pvt Ltd</general><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>198610</creationdate><title>Anti - diabetic activity of the seed kernel of syzygium cumini linn</title><author>Nair, R B ; Santhakumari, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1118-798e615f144d0aa838759a5d8d0e202b558f0d13e4219ce3e3ed47666f2f09b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Original</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nair, R B</creatorcontrib><creatorcontrib>Santhakumari, G</creatorcontrib><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Ancient science of life</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nair, R B</au><au>Santhakumari, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti - diabetic activity of the seed kernel of syzygium cumini linn</atitle><jtitle>Ancient science of life</jtitle><addtitle>Anc Sci Life</addtitle><date>1986-10</date><risdate>1986</risdate><volume>6</volume><issue>2</issue><spage>80</spage><epage>84</epage><pages>80-84</pages><issn>0257-7941</issn><eissn>2249-9547</eissn><abstract>Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also be promoting endogenous release of insulin. An extra pancreatic site of action of the drug cannot be ruled out, since it produced a significant decrease in the blood sugar level (17.04%) in alloxan diabetic rats.</abstract><cop>India</cop><pub>Medknow Publications & Media Pvt Ltd</pub><pmid>22557552</pmid><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| source | Medknow Open Access Medical Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Original |
| title | Anti - diabetic activity of the seed kernel of syzygium cumini linn |
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