Anti - diabetic activity of the seed kernel of syzygium cumini linn

Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also b...

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Veröffentlicht in:Ancient science of life 1986-10, Vol.6 (2), p.80-84
Hauptverfasser: Nair, R B, Santhakumari, G
Format: Artikel
Sprache:eng
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Zusammenfassung:Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also be promoting endogenous release of insulin. An extra pancreatic site of action of the drug cannot be ruled out, since it produced a significant decrease in the blood sugar level (17.04%) in alloxan diabetic rats.
ISSN:0257-7941
2249-9547