Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats
Acupuncture was used to treat symptoms of pain in the ancient orient. The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recor...
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| Veröffentlicht in: | Evidence-based complementary and alternative medicine 2012-01, Vol.2012 (2012), p.1-7 |
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| creator | Lee, Hyejung Shim, Insop Won, Ran Chang, Kyung-Ha Lee, Bae Hwan |
| description | Acupuncture was used to treat symptoms of pain in the ancient orient. The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recorded using a video camera and c-Fos immunohistochemistry was performed thereafter. Treatment of EA at BL60 significantly inhibited flinching behavior and c-fos expression induced by formalin injection into the paw, compared to a control group. These results suggest that electroacupuncture at BL60 acupoint may be effective in relieving inflammatory pain. |
| doi_str_mv | 10.1155/2012/324039 |
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The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recorded using a video camera and c-Fos immunohistochemistry was performed thereafter. Treatment of EA at BL60 significantly inhibited flinching behavior and c-fos expression induced by formalin injection into the paw, compared to a control group. These results suggest that electroacupuncture at BL60 acupoint may be effective in relieving inflammatory pain.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2012/324039</identifier><identifier>PMID: 22550540</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Acupuncture ; Analgesics ; Behavior ; Brain research ; c-Fos protein ; Electroacupuncture ; Experiments ; Formaldehyde ; Immunohistochemistry ; Inflammation ; Injection ; Narcotics ; Nervous system ; Neurosciences ; Pain ; Pain perception ; Rats ; Rodents ; Spinal cord</subject><ispartof>Evidence-based complementary and alternative medicine, 2012-01, Vol.2012 (2012), p.1-7</ispartof><rights>Copyright © 2012 Kyung-Ha Chang et al.</rights><rights>Copyright © 2012 Kyung-Ha Chang et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2012 Kyung-Ha Chang et al. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c467t-212d1ed9e42e1b894fe7d23b1d091a43d92b77262420895c2acb3cb186ea215d3</citedby><cites>FETCH-LOGICAL-c467t-212d1ed9e42e1b894fe7d23b1d091a43d92b77262420895c2acb3cb186ea215d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328898/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328898/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22550540$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Liang, Fengxia</contributor><contributor>Fengxia Liang</contributor><creatorcontrib>Lee, Hyejung</creatorcontrib><creatorcontrib>Shim, Insop</creatorcontrib><creatorcontrib>Won, Ran</creatorcontrib><creatorcontrib>Chang, Kyung-Ha</creatorcontrib><creatorcontrib>Lee, Bae Hwan</creatorcontrib><title>Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>Acupuncture was used to treat symptoms of pain in the ancient orient. 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These results suggest that electroacupuncture at BL60 acupoint may be effective in relieving inflammatory pain.</description><subject>Acupuncture</subject><subject>Analgesics</subject><subject>Behavior</subject><subject>Brain research</subject><subject>c-Fos protein</subject><subject>Electroacupuncture</subject><subject>Experiments</subject><subject>Formaldehyde</subject><subject>Immunohistochemistry</subject><subject>Inflammation</subject><subject>Injection</subject><subject>Narcotics</subject><subject>Nervous system</subject><subject>Neurosciences</subject><subject>Pain</subject><subject>Pain perception</subject><subject>Rats</subject><subject>Rodents</subject><subject>Spinal cord</subject><issn>1741-427X</issn><issn>1741-4288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0c1rFDEYBvAgiv2wp95lwItUxuZ9k0wyF8GWXS0sKKLQW8gkGTtlNtkmM5b-903ZurSehEAC-fHwJg8hx0A_AghxihTwlCGnrH1B9kFyqDkq9XJ3lpd75CDna0qxlVK-JnuIQlDB6T5ZLvre2ylXsa8WYzmlaOy8mYOd5uQrM1Vnq4ZWMVTLmNZmHEJ9Edxsvau-myFUZf0wU35DXvVmzP7ocT8kv5aLn-df69W3Lxfnn1e15Y2cagR04F3rOXroVMt7Lx2yDhxtwXDmWuykxAY5UtUKi8Z2zHagGm8QhGOH5NM2dzN3a--sD1Myo96kYW3SnY5m0M9vwnClf8c_mrHyJa0qAe8fA1K8mX2e9HrI1o-jCT7OWQMFAMkahYW--4dexzmF8jyNtKGKSlCiqA9bZVPMOfl-NwxQ_dCPfuhHb_sp-u3T-Xf2byEFnGzB1RCcuR3-L80X4nvzBKNC0bB7sNOfiw</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Lee, Hyejung</creator><creator>Shim, Insop</creator><creator>Won, Ran</creator><creator>Chang, Kyung-Ha</creator><creator>Lee, Bae Hwan</creator><general>Hindawi Publishing Corporation</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120101</creationdate><title>Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats</title><author>Lee, Hyejung ; 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The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recorded using a video camera and c-Fos immunohistochemistry was performed thereafter. Treatment of EA at BL60 significantly inhibited flinching behavior and c-fos expression induced by formalin injection into the paw, compared to a control group. These results suggest that electroacupuncture at BL60 acupoint may be effective in relieving inflammatory pain.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>22550540</pmid><doi>10.1155/2012/324039</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Acupuncture Analgesics Behavior Brain research c-Fos protein Electroacupuncture Experiments Formaldehyde Immunohistochemistry Inflammation Injection Narcotics Nervous system Neurosciences Pain Pain perception Rats Rodents Spinal cord |
| title | Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats |
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