Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats

Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats

Acupuncture was used to treat symptoms of pain in the ancient orient. The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recor...

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Veröffentlicht in:Evidence-based complementary and alternative medicine 2012-01, Vol.2012 (2012), p.1-7
Hauptverfasser: Lee, Hyejung, Shim, Insop, Won, Ran, Chang, Kyung-Ha, Lee, Bae Hwan
Format: Artikel
Sprache:eng
Schlagworte:
Acupuncture
Analgesics
Behavior
Brain research
c-Fos protein
Electroacupuncture
Experiments
Formaldehyde
Immunohistochemistry
Inflammation
Injection
Narcotics
Nervous system
Neurosciences
Pain
Pain perception
Rats
Rodents
Spinal cord
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Beschreibung
Zusammenfassung:Acupuncture was used to treat symptoms of pain in the ancient orient. The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recorded using a video camera and c-Fos immunohistochemistry was performed thereafter. Treatment of EA at BL60 significantly inhibited flinching behavior and c-fos expression induced by formalin injection into the paw, compared to a control group. These results suggest that electroacupuncture at BL60 acupoint may be effective in relieving inflammatory pain.
ISSN:1741-427X
1741-4288
DOI:10.1155/2012/324039