International collaboration: a retrospective study examining the survival of Irish citizens following lung transplantation in both the UK and Ireland

ObjectivePrior to 2005, Irish citizens had exclusively availed of lung transplantation services in the UK. Since 2005, lung transplantation has been available to these patients in both the UK and Ireland. We aimed to evaluate the outcomes of Irish patients undergoing lung transplantation in both the...

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Veröffentlicht in:BMJ open 2012-01, Vol.2 (2), p.e000605-e000605
Hauptverfasser: Adamali, Huzaifa I, Judge, Eoin P, Healy, David, Nolke, Lars, Redmond, Karen C, Bartosik, Waldemar, McCarthy, Jim, Egan, Jim J
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Sprache:eng
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Zusammenfassung:ObjectivePrior to 2005, Irish citizens had exclusively availed of lung transplantation services in the UK. Since 2005, lung transplantation has been available to these patients in both the UK and Ireland. We aimed to evaluate the outcomes of Irish patients undergoing lung transplantation in both the UK and Ireland.DesignWe retrospectively examined the outcome of Irish patients transplanted in the UK and Ireland. Lung allocation score (LAS) was used as a marker of disease severity.ResultsA total of 134 patients have undergone transplantation. 102 patients underwent transplantation in the UK and 32 patients in Ireland. In total, 52% were patients with cystic fibrosis, 19% had emphysema and 15% had idiopathic pulmonary fibrosis. In Ireland, 44% of the patients suffered from idiopathic pulmonary fibrosis, 31% had emphysema and 16% had cystic fibrosis. A total of 96 double sequential transplants and 38 single transplants have been performed. LAS of all patients undergoing lung transplantation was 37.8 (±1.02). The mean LAS for patients undergoing lung transplantation in Ireland was 44.7 (±3.1), and 35 (±0.4) for patients undergoing lung transplantation in the UK (p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2011-000605