Rat brains also have a default mode network
The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function(s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonh...
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2012-03, Vol.109 (10), p.3979-3984 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function(s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonhuman primates and humans. Our data suggest that, despite the distinct evolutionary paths between rodent and primate brain, a well-organized, intrinsically coherent DMN appears to be a fundamental feature in the mammalian brain whose primary functions might be to integrate multimodal sensory and affective information to guide behavior in anticipation of changing environmental contingencies. |
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ISSN: | 0027-8424 1091-6490 |
DOI: | 10.1073/pnas.1200506109 |