17β-Estradiol Represses Myogenic Differentiation by Increasing Ubiquitin-specific Peptidase 19 through Estrogen Receptor α

Skeletal muscles express estrogen receptor (ER) α and ERβ. However, the roles of estrogens acting through the ERs in skeletal muscles remain unclear. The effects of 17β-estradiol (E2) on myogenesis were studied in C2C12 myoblasts. E2 and an ERα-selective agonist propylpyrazole-triol depressed myosin...

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Veröffentlicht in:The Journal of biological chemistry 2011-12, Vol.286 (48), p.41455-41465
Hauptverfasser: Ogawa, Masahiro, Yamaji, Ryoichi, Higashimura, Yasuki, Harada, Naoki, Ashida, Hitoshi, Nakano, Yoshihisa, Inui, Hiroshi
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Sprache:eng
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