Human retina D2 receptor cDNAs have multiple polyadenylation sites and differ from a pituitary clone at the 5' non-coding region

An oligonucleotide probe, based on the rat brain D2 receptor cDNA was used to isolate two clones (11.1 and 11.2) from a human retina cDNA library. Their coding sequence displayed almost 100% homology with the corresponding region of a previously published D2 receptor cDNA clone isolated from human p...

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Veröffentlicht in:Nucleic acids research 1990-03, Vol.18 (5), p.1299-1299
Hauptverfasser: ROBAKIS, N. K, MOHAMADI, M, DING YI FU, KUMAR SAMBAMURTI, REFOLO, L. M
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container_issue 5
container_start_page 1299
container_title Nucleic acids research
container_volume 18
creator ROBAKIS, N. K
MOHAMADI, M
DING YI FU
KUMAR SAMBAMURTI
REFOLO, L. M
description An oligonucleotide probe, based on the rat brain D2 receptor cDNA was used to isolate two clones (11.1 and 11.2) from a human retina cDNA library. Their coding sequence displayed almost 100% homology with the corresponding region of a previously published D2 receptor cDNA clone isolated from human pituitary. The first 45 bp of the 5' non-coding region of clone 11.1 differ from the corresponding region of pituitary clone 14.1 indicating that the two cDNAs are splicing variants.
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source MEDLINE; Oxford University Press Journals Digital Archive Legacy; PubMed Central
subjects Amino Acid Sequence
Base Sequence
Biological and medical sciences
DNA - genetics
DNA - metabolism
dopamine
Fundamental and applied biological sciences. Psychology
genes
Genes. Genome
Humans
Introns
Molecular and cellular biology
Molecular genetics
Molecular Sequence Data
Pituitary Gland - metabolism
Poly A - metabolism
Receptors, Dopamine - genetics
Receptors, Dopamine D2
Retina - metabolism
Sequence Homology, Nucleic Acid
title Human retina D2 receptor cDNAs have multiple polyadenylation sites and differ from a pituitary clone at the 5' non-coding region
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