Human retina D2 receptor cDNAs have multiple polyadenylation sites and differ from a pituitary clone at the 5' non-coding region

An oligonucleotide probe, based on the rat brain D2 receptor cDNA was used to isolate two clones (11.1 and 11.2) from a human retina cDNA library. Their coding sequence displayed almost 100% homology with the corresponding region of a previously published D2 receptor cDNA clone isolated from human p...

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Veröffentlicht in:	Nucleic acids research 1990-03, Vol.18 (5), p.1299-1299
Hauptverfasser:	ROBAKIS, N. K, MOHAMADI, M, DING YI FU, KUMAR SAMBAMURTI, REFOLO, L. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Biological and medical sciences DNA - genetics DNA - metabolism dopamine Fundamental and applied biological sciences. Psychology genes Genes. Genome Humans Introns Molecular and cellular biology Molecular genetics Molecular Sequence Data Pituitary Gland - metabolism Poly A - metabolism Receptors, Dopamine - genetics Receptors, Dopamine D2 Retina - metabolism Sequence Homology, Nucleic Acid
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Zusammenfassung:	An oligonucleotide probe, based on the rat brain D2 receptor cDNA was used to isolate two clones (11.1 and 11.2) from a human retina cDNA library. Their coding sequence displayed almost 100% homology with the corresponding region of a previously published D2 receptor cDNA clone isolated from human pituitary. The first 45 bp of the 5' non-coding region of clone 11.1 differ from the corresponding region of pituitary clone 14.1 indicating that the two cDNAs are splicing variants.
ISSN:	0305-1048 1362-4962
DOI:	10.1093/nar/18.5.1299