Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction

Patients with CAD and LV dysfunction were assigned to receive either medical therapy alone or medical therapy plus CABG. There was no evidence of significant interaction between myocardial viability and treatment assignment. Coronary artery disease is an important contributor to the rise in the prev...

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Veröffentlicht in:The New England journal of medicine 2011-04, Vol.364 (17), p.1617-1625
Hauptverfasser: Bonow, Robert O, Maurer, Gerald, Lee, Kerry L, Holly, Thomas A, Binkley, Philip F, Desvigne-Nickens, Patrice, Drozdz, Jaroslaw, Farsky, Pedro S, Feldman, Arthur M, Doenst, Torsten, Michler, Robert E, Berman, Daniel S, Nicolau, Jose C, Pellikka, Patricia A, Wrobel, Krzysztof, Alotti, Nasri, Asch, Federico M, Favaloro, Liliana E, She, Lilin, Velazquez, Eric J, Jones, Robert H, Panza, Julio A
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Sprache:eng
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Zusammenfassung:Patients with CAD and LV dysfunction were assigned to receive either medical therapy alone or medical therapy plus CABG. There was no evidence of significant interaction between myocardial viability and treatment assignment. Coronary artery disease is an important contributor to the rise in the prevalence of heart failure and in associated mortality and morbidity. 1 – 4 It has not been clearly established whether coronary-artery bypass grafting (CABG) has a role in improving the symptoms and the rate of survival of patients with coronary artery disease and heart failure. We conducted the multicenter Surgical Treatment for Ischemic Heart Failure (STICH) trial 5 , 6 to examine two hypotheses, one of which (hypothesis 1) compared the efficacy of medical therapy alone with that of medical therapy plus CABG in patients with coronary artery disease and left ventricular . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1100358