Prevention of mother-to-child transmission of human immunodeficiency virus among pregnant women using injecting drugs in Ukraine, 2000-10

ABSTRACT Aims To compare clinical status, mother‐to‐child transmission (MTCT) rates, use of prevention of (PMTCT) interventions and pregnancy outcomes between HIV‐infected injecting drug users (IDUs) and non‐IDUs. Design and setting Prospective cohort study conducted in seven human immunodeficienc...

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Veröffentlicht in:	Addiction (Abingdon, England) England), 2012-01, Vol.107 (1), p.118-128
Hauptverfasser:	Thorne, Claire, Semenenko, Igor, Malyuta, Ruslan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immune Deficiency Syndrome Addictive behaviors Adult Adult and adolescent clinical studies AIDS Analgesics, Opioid Anti-Retroviral Agents - therapeutic use Antiretroviral Therapy, Highly Active - statistics & numerical data Biological and medical sciences CD4 Lymphocyte Count Comparative analysis Disease prevention Disease transmission Drug Abuse Drug addiction Drug use Drug users Female Females Health Status Healthcare Disparities HIV HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - prevention & control HIV Infections - transmission Human immunodeficiency virus Humans Infant, Low Birth Weight Infant, Newborn Infants Infectious Disease Transmission, Vertical - prevention & control Infectious Disease Transmission, Vertical - statistics & numerical data injecting drugs Male Maternal & child health Medical sciences Miscellaneous mother-to-child Mothers Post-Exposure Prophylaxis - methods Post-Exposure Prophylaxis - statistics & numerical data Pregnancy Pregnancy Complications, Infectious - drug therapy Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - prevention & control Pregnancy Outcome pregnancy outcomes Prevention Prevention and actions Prospective Studies Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Public health. Hygiene Public health. Hygiene-occupational medicine Research Reports Risk Risk Factors Substance Abuse, Intravenous - epidemiology transmission Ukraine Ukraine - epidemiology Young Adult
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Zusammenfassung:	ABSTRACT Aims To compare clinical status, mother‐to‐child transmission (MTCT) rates, use of prevention of (PMTCT) interventions and pregnancy outcomes between HIV‐infected injecting drug users (IDUs) and non‐IDUs. Design and setting Prospective cohort study conducted in seven human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) Centres in Ukraine, 2000–10. Participants Pregnant HIV‐infected women, identified before/during pregnancy or intrapartum, and their live‐born infants (n = 6200); 1028 women followed post‐partum. Measurements Maternal and delivery characteristics, PMTCT prophylaxis, MTCT rates, preterm delivery (PTD) and low birth weight (LBW). Findings Of 6200 women, 1111 (18%) reported current/previous IDU. The proportion of IDUs diagnosed with HIV before conception increased from 31% in 2000/01 to 60% in 2008/09 (P
ISSN:	0965-2140 1360-0443
DOI:	10.1111/j.1360-0443.2011.03609.x