Centering of organic-inorganic hybrid liposomal cerasomes in electrospun gelatin nanofibers

A study investigating the embedding of stabilized organic-inorganic liposomal cerasomes in gelatin nanofibers through the electrospinning of cerasome-dispersed gelatin aqueous solution is presented. Fluorescent and transmission electron microscopy confirm the embedding and centering of cerasomes in...

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Veröffentlicht in:Applied physics letters 2012-01, Vol.100 (3), p.033702-033702-3
Hauptverfasser: Zha, Zhengbao, Leung, Siu Ling, Dai, Zhifei, Wu, Xiaoyi
Format: Artikel
Sprache:eng
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Zusammenfassung:A study investigating the embedding of stabilized organic-inorganic liposomal cerasomes in gelatin nanofibers through the electrospinning of cerasome-dispersed gelatin aqueous solution is presented. Fluorescent and transmission electron microscopy confirm the embedding and centering of cerasomes in the electrospun nanofibers. A simple mechanism is proposed for the centering of cerasomes in gelatin nanofibers. The ability to incorporate cerasomes capable of encapsulating a variety of bioactive molecules provides a promising method to functionalize polymer nanofibers.
ISSN:0003-6951
1077-3118
0003-6951
DOI:10.1063/1.3678040