Severe diffuse obstructive coronary artery disease in an infant

Severe diffuse obstruction of the coronary arteries was diagnosed in an 18-month-old girl who presented with signs and symptoms of severe congestive cardiomyopathy. Most reported cases of myocardial infarction in neonates or infants have been secondary to obstruction of a single major coronary artery owing to thrombosis or embolism; diffuse multiple obstruction involving the entire coronary artery system, as in our case, has not previously been described. Although the exact cause of the obstruction remained unknown, the most likely mechanism was in situ thrombosis.