Telomere flip-flop: an unfolding passage to senescence

Telomere flip-flop: an unfolding passage to senescence

In this issue of EMBO reports , insight is provided into how telomeres can function both as tumour suppressors by limiting the number of times a cell can divide and as tumour promoters by allowing genomic instability.

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Bibliographische Detailangaben
Veröffentlicht in:EMBO reports 2012-01, Vol.13 (1), p.5-6
1. Verfasser: Price, Carolyn M
Format: Artikel
Sprache:eng
Schlagworte:
Cellular Senescence - genetics
EMBO06
EMBO13
Genomes
Hot off the Press
Humans
Telomerase
Telomere - metabolism
Tumors
Upfront
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:In this issue of EMBO reports , insight is provided into how telomeres can function both as tumour suppressors by limiting the number of times a cell can divide and as tumour promoters by allowing genomic instability.
ISSN:1469-221X
1469-3178
DOI:10.1038/embor.2011.237