Osmolar therapy in pediatric traumatic brain injury

To describe patterns of use for mannitol and hypertonic saline in children with traumatic brain injury, to evaluate any potential associations between hypertonic saline and mannitol use and patient demographic, injury, and treatment hospital characteristics, and to determine whether the 2003 guideli...

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Veröffentlicht in:	Critical care medicine 2012, Vol.40 (1), p.208-215
Hauptverfasser:	BENNETT, Tellen D, STATLER, Kimberly D, KENT KORGENSKI, E, BRATTON, Susan L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Factors Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Brain Injuries - drug therapy Brain Injuries - therapy Child Child, Preschool Emergency and intensive care: neonates and children. Prematurity. Sudden death Female Fluid Therapy - methods Humans Infant Infant, Newborn Injury Severity Score Intensive care medicine Intracranial Pressure - drug effects Male Mannitol - administration & dosage Mannitol - therapeutic use Medical sciences Retrospective Studies Saline Solution, Hypertonic - therapeutic use Treatment Outcome
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Zusammenfassung:	To describe patterns of use for mannitol and hypertonic saline in children with traumatic brain injury, to evaluate any potential associations between hypertonic saline and mannitol use and patient demographic, injury, and treatment hospital characteristics, and to determine whether the 2003 guidelines for severe pediatric traumatic brain injury impacted clinical practice regarding osmolar therapy. Retrospective cohort study. Pediatric Health Information System database, January, 2001 to December, 2008. Children (age
ISSN:	0090-3493 1530-0293
DOI:	10.1097/CCM.0b013e31822e9d31