Microcrimped Collagen Fiber-Elastin Composites

Microcrimped Collagen Fiber-Elastin Composites

A flexible membrane templating technique (a) is developed for the fabrication of microcrimped collagen microfibers (b) that are embedded in an elastin‐like protein matrix to generate hierarchical, biologically inspired fiber‐reinforced composites (c). The microcrimped structure is stable under cycli...

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Veröffentlicht in:Advanced materials (Weinheim) 2010-05, Vol.22 (18), p.2041-2044
Hauptverfasser: Caves, Jeffrey M., Kumar, Vivek A., Xu, Wenjun, Naik, Nisarga, Allen, Mark G., Chaikof, Elliot L.
Format: Artikel
Sprache:eng
Schlagworte:
Biocompatible Materials - chemistry
Biomedical applications
Biomimetics
Collagen - chemistry
Composite materials
Elastin - chemistry
Microscopy, Confocal
Microstructures
Tissue engineering
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Zusammenfassung:A flexible membrane templating technique (a) is developed for the fabrication of microcrimped collagen microfibers (b) that are embedded in an elastin‐like protein matrix to generate hierarchical, biologically inspired fiber‐reinforced composites (c). The microcrimped structure is stable under cyclic loading and the mechanical response of the engineered collagen‐elastin composite mimics that of native tissue.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200903612