Diagnosis of Diabetes using Hemoglobin A1c: Should Recommendations in Adults Be Extrapolated to Adolescents?

Objective To compare test performance of hemoglobin A1c (HbA1c) for detecting diabetes mellitus/pre-diabetes for adolescents versus adults in the United States. Study design Individuals were defined as having diabetes mellitus (fasting plasma glucose [FPG] ≥126 mg/dL; 2-hour plasma glucose (2-hr PG)...

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Veröffentlicht in:	The Journal of pediatrics 2011-06, Vol.158 (6), p.947-952.e3
Hauptverfasser:	Lee, Joyce M., MD, MPH, Wu, En-Ling, BA, Tarini, Beth, MD, MS, Herman, William H., MD, MPH, Yoon, Esther, MD, MPH
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent adolescents Adult adults Aged Biological and medical sciences blood glucose Blood Glucose - metabolism Child Cross-Sectional Studies diabetes mellitus Diabetes Mellitus - blood Diabetes Mellitus - diagnosis Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance fasting Female General aspects Glycated Hemoglobin A - analysis glycohemoglobin Humans Male Medical sciences Middle Aged Nutrition Surveys Pediatrics ROC Curve Sensitivity and Specificity United States
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Zusammenfassung:	Objective To compare test performance of hemoglobin A1c (HbA1c) for detecting diabetes mellitus/pre-diabetes for adolescents versus adults in the United States. Study design Individuals were defined as having diabetes mellitus (fasting plasma glucose [FPG] ≥126 mg/dL; 2-hour plasma glucose (2-hr PG) ≥200 mg/dL) or pre-diabetes (100 ≤ FPG
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2010.11.026