Adsorption of Essential Micronutrients by Carbon Nanotubes and the Implications for Nanotoxicity Testing

Hungry nanotubes: Single‐walled carbon nanotubes (SWNTs) compete with cells by interacting with folate and other essential micronutrients in cell culture medium (see picture). Sequestering of folate can cause apparent toxicity even without direct nanotube–cell contact through a new “starvation” mech...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2008-06, Vol.4 (6), p.721-727
Hauptverfasser:	Guo, Lin, Von Dem Bussche, Annette, Buechner, Michelle, Yan, Aihui, Kane, Agnes B., Hurt, Robert H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption amino acids Amino Acids - metabolism biological activity carbon nanotubes Cell Line Cell Survival - drug effects Culture Media - metabolism Humans Microscopy, Electron, Transmission Nanotubes, Carbon - toxicity Toxicity Tests toxicology vitamins Vitamins - metabolism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Hungry nanotubes: Single‐walled carbon nanotubes (SWNTs) compete with cells by interacting with folate and other essential micronutrients in cell culture medium (see picture). Sequestering of folate can cause apparent toxicity even without direct nanotube–cell contact through a new “starvation” mechanism.
ISSN:	1613-6810 1613-6829
DOI:	10.1002/smll.200700754