Semaphorin Breaks Symmetry

Axon-dendrite polarity is likely instructed by extrinsic cues in the developing nervous system, though the mechanisms governing this process remain to be fully elucidated. In this issue of Neuron, Shelly et al. show that the axon guidance cue Semaphorin 3A can promote dendrite growth by inhibiting a...

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Veröffentlicht in:Neuron (Cambridge, Mass.) Mass.), 2011-08, Vol.71 (3), p.381-382
Hauptverfasser: Howell, Audrey S., Shen, Kang
Format: Artikel
Sprache:eng
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Zusammenfassung:Axon-dendrite polarity is likely instructed by extrinsic cues in the developing nervous system, though the mechanisms governing this process remain to be fully elucidated. In this issue of Neuron, Shelly et al. show that the axon guidance cue Semaphorin 3A can promote dendrite growth by inhibiting axon specification.
ISSN:0896-6273
1097-4199
DOI:10.1016/j.neuron.2011.07.020