Total Synthesis of the Natural Product (±)-Dibromophakellin and Analogues
(±)-Dibromophakellin has been synthesized in two steps from a known alkene intermediate. The key step in the synthesis is the NBS olefin activation to facilitate the addition of a guanidine molecule across the double bond.
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| Veröffentlicht in: | Organic letters 2011-09, Vol.13 (17), p.4550-4553 |
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| container_title | Organic letters |
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| creator | Hewlett, Nicole M Tepe, Jetze J |
| description | (±)-Dibromophakellin has been synthesized in two steps from a known alkene intermediate. The key step in the synthesis is the NBS olefin activation to facilitate the addition of a guanidine molecule across the double bond. |
| doi_str_mv | 10.1021/ol201741r |
| format | Article |
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| ispartof | Organic letters, 2011-09, Vol.13 (17), p.4550-4553 |
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| language | eng |
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| source | MEDLINE; ACS Journals: American Chemical Society Web Editions |
| subjects | Biological Factors - chemical synthesis Biological Factors - chemistry Heterocyclic Compounds, 4 or More Rings - chemical synthesis Heterocyclic Compounds, 4 or More Rings - chemistry Molecular Structure Stereoisomerism |
| title | Total Synthesis of the Natural Product (±)-Dibromophakellin and Analogues |
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