Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous System

Lipid transmitters and the role of the endocannabinoid system in neurological signalling are discussed. The process by which enzymes synthesize endocannabinoids and anandamide is explored.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2008-05, Vol.108 (5), p.1687-1707
Hauptverfasser:	Ahn, Kay, McKinney, Michele K, Cravatt, Benjamin F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acids - chemistry Arachidonic Acids - metabolism Biochemistry Cannabinoid Receptor Modulators - chemistry Cannabinoid Receptor Modulators - metabolism Chemical synthesis Endocannabinoids Enzymes - metabolism Humans Lipids Nervous System - metabolism Neurology Polyunsaturated Alkamides - chemistry Polyunsaturated Alkamides - metabolism Signal Transduction
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Beschreibung
Zusammenfassung:	Lipid transmitters and the role of the endocannabinoid system in neurological signalling are discussed. The process by which enzymes synthesize endocannabinoids and anandamide is explored.
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr0782067