Cytotoxic essential oil from Annona sengalensis Pers. leaves

The cytotoxicity against brine shrimp of the essential oil obtained from the leaves of Annona senegalensis Pers. (Annonaceae) was studied. The confirmation of this toxicity has been done by using selected tumor cell lines (A549, HT29, MCF 7, RPMI, and U251). The results showed that the total oil and...

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Veröffentlicht in:	Pharmacognosy research 2010-07, Vol.2 (4), p.211-214
Hauptverfasser:	Ahmed, A L, Bassem, S E M, Mohamed, Y H, Gamila, M W
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical properties Essences and essential oils Health aspects Magnoliidae Mass spectrometry Methods Original
Online-Zugang:	Volltext
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Zusammenfassung:	The cytotoxicity against brine shrimp of the essential oil obtained from the leaves of Annona senegalensis Pers. (Annonaceae) was studied. The confirmation of this toxicity has been done by using selected tumor cell lines (A549, HT29, MCF 7, RPMI, and U251). The results showed that the total oil and its fractions have showed mild to moderate cytotoxicity in brine shrimp lethality bioassay with LC50 = 27.3 μg/ml, and against some human tumor cell lines. The total oil and its fractions were analyzed by gas chromatography/mass spectroscopy (GC/MS). Seventy three compounds were identified.
ISSN:	0974-8490 0976-4836 0974-8490
DOI:	10.4103/0974-8490.69105