Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome

We present a high-resolution bacterial contig map of 3.4 Mb of genomic DNA in human chromosome 21q11-q21, encompassing the region of elevated disomic homozygosity in Down Syndrome-associated abnormal myelopoiesis and leukemia, as well as the markers, which has shown a strong association with Alzheim...

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Veröffentlicht in:	Genome research 1998-04, Vol.8 (4), p.385-398
Hauptverfasser:	Groet, J, Ives, J H, South, A P, Baptista, P R, Jones, T A, Yaspo, M L, Lehrach, H, Potier, M C, Van Broeckhoven, C, Nizetić, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Bacteriophage P1 - genetics Blotting, Southern Chromosome Mapping Chromosomes, Artificial, Yeast - genetics Chromosomes, Bacterial - genetics Chromosomes, Human, Pair 21 - genetics DNA, Bacterial - analysis Down Syndrome - genetics Genes Humans Letters Leukopoiesis - genetics Restriction Mapping Sequence Homology, Nucleic Acid
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