HIV-1 infection and alcohol abuse: Neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions

Highlight ► This review aims to present the mechanisms of the combined effects of HIV-1 and alcohol abuse in the brain and to discuss neuroportective therapies.

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Bibliographische Detailangaben
Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2011-06, Vol.25 (Suppl 1), p.S61-S70
Hauptverfasser:	Persidsky, Yuri, Ho, Wenzhe, Ramirez, Servio H, Potula, Raghava, Abood, Mary E, Unterwald, Ellen, Tuma, Ronald
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol abuse Alcoholism - complications Alcoholism - pathology Allergy and Immunology Blood–brain barrier Brain - pathology Cannabinoid receptor 2 Cognition Glial cells HIV Infections - complications HIV Infections - pathology HIV-1 Human immunodeficiency virus 1 Humans Nerve Degeneration - complications Nerve Degeneration - pathology Neuroinflammation Psychiatry
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Beschreibung
Zusammenfassung:	Highlight ► This review aims to present the mechanisms of the combined effects of HIV-1 and alcohol abuse in the brain and to discuss neuroportective therapies.
ISSN:	0889-1591 1090-2139
DOI:	10.1016/j.bbi.2011.03.001