Congenital diaphragmatic hernia in the preterm infant

Congenital diaphragmatic hernia in the preterm infant

Background Congenital diaphragmatic hernia (CDH) remains a significant cause of death in newborns. With advances in neonatal critical care and ventilation strategies, survival in the term infant now exceeds 80% in some centers. Although prematurity is a significant risk factor for morbidity and mort...

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Veröffentlicht in:Surgery 2010-08, Vol.148 (2), p.404-410
Hauptverfasser: Tsao, KuoJen, MD, Allison, Nathan D., MD, Harting, Matthew T., MD, Lally, Pamela A., MD, Lally, Kevin P., MD, MS
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Extracorporeal Membrane Oxygenation
Female
General aspects
Gestational Age
Hernia, Diaphragmatic - mortality
Hernia, Diaphragmatic - surgery
Hernias, Diaphragmatic, Congenital
Humans
Infant, Newborn
Infant, Premature
Male
Medical sciences
Odds Ratio
Pregnancy
Prognosis
Prospective Studies
Registries
Surgery
Survival Analysis
Treatment Outcome
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Zusammenfassung:Background Congenital diaphragmatic hernia (CDH) remains a significant cause of death in newborns. With advances in neonatal critical care and ventilation strategies, survival in the term infant now exceeds 80% in some centers. Although prematurity is a significant risk factor for morbidity and mortality in most neonatal diseases, its associated risk with infants with CDH has been described poorly. We sought to determine the impact of prematurity on survival using data from the Congenital Diaphragmatic Hernia Registry (CDHR). Methods Prospectively collected data from live-born infants with CDH were analyzed from the CDHR from January 1995 to July 2009. Preterm infants were defined as
ISSN:0039-6060
1532-7361
DOI:10.1016/j.surg.2010.03.018