Use of α2-Agonists in Neuroanesthesia: An Overview

Use of α2-Agonists in Neuroanesthesia: An Overview

α2-Agonists are a novel class of drugs with mechanisms of action that differ from other commonly used anesthetic drugs. They have neuroprotective, cardioprotective, and sedative effects. These unique characteristics make them potentially useful during neuroanesthesia and intensive care. We review th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Ochsner journal 2011, Vol.11 (1), p.57-69
Hauptverfasser: Farag, Ehab, Argalious, Maged, Sessler, Daniel I, Kurz, Andrea, Ebrahim, Zeyd Y, Schubert, Armin
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia
Anesthesiology
Apoptosis
Hypoxia
Intensive care
Ischemia
Kinases
Metabolism
Proteins
Rodents
Traumatic brain injury
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:α2-Agonists are a novel class of drugs with mechanisms of action that differ from other commonly used anesthetic drugs. They have neuroprotective, cardioprotective, and sedative effects. These unique characteristics make them potentially useful during neuroanesthesia and intensive care. We review the effects of dexmedetomidine on cerebral blood flow and cerebral metabolism, along with recent advances in using α2-agonists in neuroanesthesia and neurointensive care.
ISSN:1524-5012