Efficacy and complications of neurosurgical treatment of acromegaly

Efficacy and complications of neurosurgical treatment of acromegaly

The aim of the study was to evaluate the frequency of occurrence of pituitary failure following neurosurgery and the efficacy of transsphenoidal tumour resection in acromegalic patients. We retrospectively evaluated 85 patients (60 female and 25 male), of mean age 43.9 ± 13.2 years, treated by trans...

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Veröffentlicht in:Pituitary 2011-06, Vol.14 (2), p.157-162
Hauptverfasser: Krzentowska-Korek, Anna, Gołkowski, Filip, Bałdys-Waligórska, Agata, Hubalewska-Dydejczyk, Alicja
Format: Artikel
Sprache:eng
Schlagworte:
Acromegaly - blood
Acromegaly - epidemiology
Acromegaly - etiology
Acromegaly - surgery
Adenoma - complications
Adenoma - epidemiology
Adenoma - pathology
Adenoma - surgery
Adult
Endocrinology
Female
Growth Hormone-Secreting Pituitary Adenoma - complications
Growth Hormone-Secreting Pituitary Adenoma - epidemiology
Growth Hormone-Secreting Pituitary Adenoma - pathology
Growth Hormone-Secreting Pituitary Adenoma - surgery
Human Growth Hormone - blood
Human Physiology
Humans
Insulin-Like Growth Factor I - analysis
Male
Medicine
Medicine & Public Health
Middle Aged
Neurosurgical Procedures - adverse effects
Neurosurgical Procedures - rehabilitation
Neurosurgical Procedures - statistics & numerical data
Postoperative Complications - epidemiology
Retrospective Studies
Treatment Outcome
Tumor Burden
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Zusammenfassung:The aim of the study was to evaluate the frequency of occurrence of pituitary failure following neurosurgery and the efficacy of transsphenoidal tumour resection in acromegalic patients. We retrospectively evaluated 85 patients (60 female and 25 male), of mean age 43.9 ± 13.2 years, treated by transsphenoidal neurosurgery. Macroadenoma and microadenoma of pituitary were found in 66 (77.6%) and 19 (22.4%) of these patients, respectively. Criteria of cure following neurosurgery were: basal GH 
ISSN:1386-341X
1573-7403
DOI:10.1007/s11102-010-0273-0