PARP Inhibitors in Cancer Therapy: Promise, Progress, and Puzzles
A recent article in the New England Journal of Medicine by O'Shaughnessy et al. provides evidence that a treatment strategy aimed at inducing DNA damage with chemotherapy while simultaneously disabling repair using a PARP inhibitor might offer hope for patients with a treatment-refractory form...
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| Veröffentlicht in: | Cancer cell 2011-02, Vol.19 (2), p.165-167 |
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| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A recent article in the
New England Journal of Medicine by O'Shaughnessy et al. provides evidence that a treatment strategy aimed at inducing DNA damage with chemotherapy while simultaneously disabling repair using a PARP inhibitor might offer hope for patients with a treatment-refractory form of breast cancer. |
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| ISSN: | 1535-6108 1878-3686 |
| DOI: | 10.1016/j.ccr.2011.01.047 |