Two Ring-A-Aromatized Bile Acids from the Marine Sponge Sollasella Moretonensis

Two ring-A-aromatized bile acids, 1 and 2, were isolated from the sponge Sollasella moretonensis, collected from the seabed of northern Queensland. Structures were assigned on the basis of extensive 1D and 2D NMR studies, as well as analysis by HRESIMS. Compound 2 has previously been produced synthe...

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Veröffentlicht in:	Natural product communications 2010-10, Vol.5 (10), p.1571-1574
Hauptverfasser:	Lu, Zhenyu, Van Wagoner, Ryan M., Harper, Mary Kay, Hooper, John N. A., Ireland, Chris M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile Acids and Salts - chemistry Bile Acids and Salts - isolation & purification Cholenes - isolation & purification Norsteroids - isolation & purification Porifera - chemistry
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Beschreibung
Zusammenfassung:	Two ring-A-aromatized bile acids, 1 and 2, were isolated from the sponge Sollasella moretonensis, collected from the seabed of northern Queensland. Structures were assigned on the basis of extensive 1D and 2D NMR studies, as well as analysis by HRESIMS. Compound 2 has previously been produced synthetically, though this marks its first isolation from a natural source.
ISSN:	1934-578X 1555-9475
DOI:	10.1177/1934578X1000501011