Neuro-regression in vitamin B12 deficiency

Neuro-regression in vitamin B12 deficiency

Neuroregression in infants has varied aetiology and vitamin B12 deficiency is one of the uncommon causes. Infantile vitamin B12 deficiency is encountered in malnourished infants or in offspring of strict vegan mothers. We present two cases, both infants of 10 and 8 months of age, whose mothers had v...

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Veröffentlicht in:BMJ case reports 2009, Vol.2009 (mar08 1), p.bcr0620080235-bcr0620080235
Hauptverfasser: Agrawal, Sanwar, Nathani, Shweta
Format: Artikel
Sprache:eng
Schlagworte:
12 Months
Age
Anemia
Asia
Atrophy
Breastfeeding & lactation
Dairy products
Female
Hemoglobin
Indian Sub-Continent
Leukocytes
Male
Rare Disease
Vegetarianism
Vitamin deficiency
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Zusammenfassung:Neuroregression in infants has varied aetiology and vitamin B12 deficiency is one of the uncommon causes. Infantile vitamin B12 deficiency is encountered in malnourished infants or in offspring of strict vegan mothers. We present two cases, both infants of 10 and 8 months of age, whose mothers had vitamin B12 deficiency. On admission, the patients were apathic, hypotonic and lethargic. Serum vitamin B12 levels were below normal limits. On cranial MRI, T2-weighted images revealed frontoparietal cortical atrophy. Both the infants responded to vitamin B12 treatment.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr.06.2008.0235