Spacecraft bacterium, Paenibacillus pasadenensis, causing wound infection in humans

In a patient with mediastinitis after cardiac surgery Paenibacillus pasadenensis was detected in his sternal wound. Paenibacilli are gram-positive, aerobic, bacteria related to bacilli. Until recently these organisms were not known to cause human disease. A few cases of human infection caused by ano...

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Veröffentlicht in:BMJ case reports 2010-12, Vol.2010 (dec21 1), p.bcr0620103058-bcr0620103058
Hauptverfasser: Anikpeh, Y Flammer, Keller, P, Bloemberg, GV, Grünenfelder, J, Zinkernagel, A S
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Sprache:eng
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Zusammenfassung:In a patient with mediastinitis after cardiac surgery Paenibacillus pasadenensis was detected in his sternal wound. Paenibacilli are gram-positive, aerobic, bacteria related to bacilli. Until recently these organisms were not known to cause human disease. A few cases of human infection caused by another member of this genus, P alvei, have been reported. The authors describe the first infection with P pasadenensis in humans. P pasadenensis was detected by broad-range bacterial 16S rRNA PCR. Treatment consisted of surgical debridement and antibiotics, vancomycin and ciprofloxacin followed by clindamycin and ciprofloxacin, resulting in complete recovery.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr.06.2010.3058