Chronic Kidney Disease After Hematopoietic Stem Cell Transplantation

Summary Acute and chronic kidney diseases occur after hematopoietic stem cell transplantation. These are caused by the transplant itself, and the complications of transplant. Recent estimates show that near 15% of subjects undergoing hematopoietic stem cell transplantation will develop chronic kidne...

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Veröffentlicht in:	Seminars in nephrology 2010-11, Vol.30 (6), p.627-634
Hauptverfasser:	Cohen, Eric P., MD, Pais, Priya, MD, Moulder, John E., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals chronic kidney disease Hematopoietic stem cell transplant Hematopoietic Stem Cell Transplantation - adverse effects Humans Kidney Diseases - complications Kidney Transplantation mitigation Nephrology prevention radiation nephropathy Renal Insufficiency, Chronic - diagnosis Renal Insufficiency, Chronic - epidemiology Renal Insufficiency, Chronic - etiology Renal Insufficiency, Chronic - therapy treatment Whole-Body Irradiation - adverse effects
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Beschreibung
Zusammenfassung:	Summary Acute and chronic kidney diseases occur after hematopoietic stem cell transplantation. These are caused by the transplant itself, and the complications of transplant. Recent estimates show that near 15% of subjects undergoing hematopoietic stem cell transplantation will develop chronic kidney disease, which is a complication rate that can affect outcome and reduce survival. Investigation of the causes of chronic kidney disease is needed, as are ways to prevent, mitigate, and treat it.
ISSN:	0270-9295 1558-4488
DOI:	10.1016/j.semnephrol.2010.09.010