Platelet precursors display bipolar behavior

Platelet precursors display bipolar behavior

In this issue, Thon et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201006102) demonstrate that newly released platelets exhibit bipolar behavior, shifting back and forth between round cells and multibodied proplatelets (Thon et al., 2010). The authors define this intermediate as a preplatelet and, in...

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Veröffentlicht in:The Journal of cell biology 2010-11, Vol.191 (4), p.699-700
Hauptverfasser: Schwertz, Hansjörg, Weyrich, Andrew S
Format: Artikel
Sprache:eng
Schlagworte:
Blood
Blood platelets
Blood Platelets - cytology
Blood Platelets - physiology
Cell Differentiation - physiology
Cellular biology
Comment
Humans
Maturation
Megakaryocytes
Platelets
Reviews
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Zusammenfassung:In this issue, Thon et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201006102) demonstrate that newly released platelets exhibit bipolar behavior, shifting back and forth between round cells and multibodied proplatelets (Thon et al., 2010). The authors define this intermediate as a preplatelet and, in doing so, shed new insight into the terminal steps of platelet maturation.
ISSN:0021-9525
1540-8140
DOI:10.1083/jcb.201010082