Efficient Synthesis of 1-Sulfonyl-1,2,3-triazoles

An efficient room-temperature method for the synthesis of 1-sulfonyl-1,2,3-triazoles from in situ generated copper(I) acetylides and sulfonyl azides is described. The copper(I) thiophene-2-carboxylate (CuTC) catalyst produces the title compounds under both nonbasic anhydrous and aqueous conditions i...

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Veröffentlicht in:	Organic letters 2010-11, Vol.12 (21), p.4952-4955
Hauptverfasser:	Raushel, Jessica, Fokin, Valery V
Format:	Artikel
Sprache:	eng
Schlagworte:	Copper - chemistry Ligands Molecular Structure Sulfones - chemistry Triazoles - chemical synthesis
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	An efficient room-temperature method for the synthesis of 1-sulfonyl-1,2,3-triazoles from in situ generated copper(I) acetylides and sulfonyl azides is described. The copper(I) thiophene-2-carboxylate (CuTC) catalyst produces the title compounds under both nonbasic anhydrous and aqueous conditions in good yields.
ISSN:	1523-7060 1523-7052
DOI:	10.1021/ol102087r