Mapping the pinhole formation pathway of S21

Summary Phage holins are small, lethal membrane proteins of two general types: canonical holins, like λ S105, which oligomerizes and forms large membrane holes of unprecedented size; and pinholins, like S2168 of lambdoid phage 21, which forms homo‐heptameric channels, or pinholes, with a lumen of

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Veröffentlicht in:Molecular microbiology 2010-11, Vol.78 (3), p.710-719
Hauptverfasser: Pang, Ting, Park, Taehyun, Young, Ry
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary Phage holins are small, lethal membrane proteins of two general types: canonical holins, like λ S105, which oligomerizes and forms large membrane holes of unprecedented size; and pinholins, like S2168 of lambdoid phage 21, which forms homo‐heptameric channels, or pinholes, with a lumen of
ISSN:0950-382X
1365-2958
DOI:10.1111/j.1365-2958.2010.07362.x