Mapping the pinhole formation pathway of S21
Summary Phage holins are small, lethal membrane proteins of two general types: canonical holins, like λ S105, which oligomerizes and forms large membrane holes of unprecedented size; and pinholins, like S2168 of lambdoid phage 21, which forms homo‐heptameric channels, or pinholes, with a lumen of
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Veröffentlicht in: | Molecular microbiology 2010-11, Vol.78 (3), p.710-719 |
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Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Summary
Phage holins are small, lethal membrane proteins of two general types: canonical holins, like λ S105, which oligomerizes and forms large membrane holes of unprecedented size; and pinholins, like S2168 of lambdoid phage 21, which forms homo‐heptameric channels, or pinholes, with a lumen of |
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ISSN: | 0950-382X 1365-2958 |
DOI: | 10.1111/j.1365-2958.2010.07362.x |