Reversing the Effects of Fragile X Syndrome
A research on how synaptic plasticity is abnormally regulated in fragile X syndrome and how this abnormality can be reversed by therapeutic interventions is presented. Fragile X syndrome is a disorder of synaptic plasticity that contributes to abnormal development and interferes with normal learning...
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| Veröffentlicht in: | Journal of the American Academy of Child and Adolescent Psychiatry 2008-08, Vol.47 (8), p.863-867 |
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| container_end_page | 867 |
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| container_issue | 8 |
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| container_title | Journal of the American Academy of Child and Adolescent Psychiatry |
| container_volume | 47 |
| creator | Ogren, Marilee P Lombroso, Paul J |
| description | A research on how synaptic plasticity is abnormally regulated in fragile X syndrome and how this abnormality can be reversed by therapeutic interventions is presented. Fragile X syndrome is a disorder of synaptic plasticity that contributes to abnormal development and interferes with normal learning and memory. |
| doi_str_mv | 10.1097/CHI.0b0 |
| format | Article |
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Fragile X syndrome is a disorder of synaptic plasticity that contributes to abnormal development and interferes with normal learning and memory.</description><identifier>ISSN: 0890-8567</identifier><identifier>EISSN: 1527-5418</identifier><identifier>DOI: 10.1097/CHI.0b0</identifier><identifier>PMID: 18645420</identifier><identifier>CODEN: JAAPEE</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Animals ; Biological and medical sciences ; Child clinical studies ; Dendrites - metabolism ; Fragile X Mental Retardation Protein - genetics ; Fragile X Syndrome - genetics ; Fragile X Syndrome - pathology ; Fragile X Syndrome - therapy ; Genetics ; Humans ; Intervention ; Learning Problems ; Medical sciences ; Memory ; Mental disorders ; Mental Retardation ; Mice ; Plastics ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychotherapy ; Receptor, Metabotropic Glutamate 5 ; Receptors, Glutamate - genetics ; Receptors, Glutamate - metabolism ; Receptors, Metabotropic Glutamate - antagonists & inhibitors ; Receptors, Metabotropic Glutamate - genetics ; RNA, Messenger - genetics ; Spinal Cord - pathology</subject><ispartof>Journal of the American Academy of Child and Adolescent Psychiatry, 2008-08, Vol.47 (8), p.863-867</ispartof><rights>2008 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Aug 2008</rights><rights>Copyright © 2008 American Academy of Child and Adolescent Psychiatry. 2008</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3990-bba234f77a11a7b0a0d17869a8a47be00a6c020a2ed71dc456496e9101ec82a13</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925,30999</link.rule.ids><backlink>$$Uhttp://eric.ed.gov/ERICWebPortal/detail?accno=EJ811044$$DView record in ERIC$$Hfree_for_read</backlink><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20569479$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18645420$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ogren, Marilee P</creatorcontrib><creatorcontrib>Lombroso, Paul J</creatorcontrib><title>Reversing the Effects of Fragile X Syndrome</title><title>Journal of the American Academy of Child and Adolescent Psychiatry</title><addtitle>J Am Acad Child Adolesc Psychiatry</addtitle><description>A research on how synaptic plasticity is abnormally regulated in fragile X syndrome and how this abnormality can be reversed by therapeutic interventions is presented. 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| fulltext | fulltext |
| identifier | ISSN: 0890-8567 |
| ispartof | Journal of the American Academy of Child and Adolescent Psychiatry, 2008-08, Vol.47 (8), p.863-867 |
| issn | 0890-8567 1527-5418 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2957622 |
| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); Access via ScienceDirect (Elsevier) |
| subjects | Animals Biological and medical sciences Child clinical studies Dendrites - metabolism Fragile X Mental Retardation Protein - genetics Fragile X Syndrome - genetics Fragile X Syndrome - pathology Fragile X Syndrome - therapy Genetics Humans Intervention Learning Problems Medical sciences Memory Mental disorders Mental Retardation Mice Plastics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychotherapy Receptor, Metabotropic Glutamate 5 Receptors, Glutamate - genetics Receptors, Glutamate - metabolism Receptors, Metabotropic Glutamate - antagonists & inhibitors Receptors, Metabotropic Glutamate - genetics RNA, Messenger - genetics Spinal Cord - pathology |
| title | Reversing the Effects of Fragile X Syndrome |
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